Desenvolvimento de métodos eletroquímicos para determinação de neurotransmissores utilizando eletrodos de zircônia nanoestruturada e diamante dopado com boro
Carregando...
Data
2014-01-28
Autores
Título da Revista
ISSN da Revista
Título de Volume
Editor
Universidade Federal de Goiás
Resumo
DSA® electrodes modified with films ErYZrO2 or YZrO2 and boron-doped diamond electrodes (BDD) were tested as electrochemical sensors detect front of the neurotransmitter epinephrine and its interfering ascorbic acid (AA) and uric acid (UA), which coexist with epinephrine in biological fluids and are also electroactive, rusting in the same potential that epinephrine. The physical and morphological characterization of the films of ZrO2 were performed using the techniques of XRD, SEM / FEG, EDXS and Open circuit potential. For electrochemical characterization of the sensor in developing were used the techniques of cyclic voltammetry (CV), differential pulse voltammetry (DPV) and Flow Injection Analysis with Amperometric Detection. The analyzes used for physical and morphological characterization of the ZrO2 films demonstrated that the technique of spin coating together with the methodology used for the deposition of ZrO2 films on the surface of substrate DSA® showed films were obtained satisfactory. The BDD electrodes showed good catalytic activity for both analyzed substances (EP, AA and UA). While BDD electrode showed good sensitivity for detection of EP in the presence of AA, electrodes ZrO2 addition to good sensitivity and selectivity showed good reproducibility for the detection of EP without interference from UA and AA.
Descrição
Palavras-chave
Epinefrina, Análise por injeção de fluxo, Técnicas voltamétricas, Eletrodos quimicamente modificados, Zirconatos, Epinephrine, Flow injection analysis, Voltammetric techniques, Zirconate, Modified electrodes
Citação
PARANHOS, Maysa de Melo. Desenvolvimento de métodos eletroquímicos para determinação de neurotransmissores utilizando eletrodos de zircônia nanoestruturada e diamante dopado com boro. 2014. 87 f. Dissertação (Mestrado em Química) - Universidade Federal de Goiás, Catalão, 2014.